Dihydrofolate Dehydrogenase
《英文msh詞典》Dihydrofolate Dehydrogenase
[同義詞] Dihydrofolate Dehydrogenase
[主題詞] Tetrahydrofolate Dehydrogenase
[中文釋義] 二氫葉酸脫氫酶
[英文釋義] An enzyme of the oxidoreductase class that catalyzes the reaction 7,8-dihyrofolate and NADPH to yield 5,6,7,8-tetrahydrofolate and NADPH+,producing reduced folate for amino acid metabolism,purine ring synthesis,and the formation of deoxythymidine monophosphate. Methotrexate and other folic acid antagonists used as chemotherapeutic drugs act by inhibiting this enzyme. (Dorland,27th ed) EC 1.5.1.3.